AU - McVean, Alistair. As the author remarks, there are scorpions and scorpions. Toxicon. Several scorpion venom toxins have been investigated for medical use. Maurotoxin Kv and SK channels blocker. Maurotoxin is a member of the α-KTx6.2 scorpion toxin family.It blocks voltage-gated potassium channels (K V 1.1/KCNA1, K V 1.2/KCNA2, and K V 1.3/KCNA3) and inhibits apamin-sensitive small conductance calcium-activated channels (SK channels), particularly K Ca 3.1 (IKca1, SK4). Abdel-Rahman MA, Omran MA, Abdel-Nabi IM, Ueda H, McVean A. Intraspecific variation in the Egyptian scorpion Scorpio maurus palmatus venom collected from different biotopes. Although its venom contains a weak neurotoxin called maurotoxin, S. maurus is not a dangerous scorpion for humans. Maurotoxin is a component of the venom of Scorpio maurus palmatus. HCV inhibitory mechanisms of the S. maurus palmatus venom.
T1 - Intraspecific variation in the Egyptian scorpion Scorpio maurus palmatus venom collected from different biotopes.
AU - Abdel-Nabi, Ismail M. AU - Ueda, Hitoshi. AU - Abdel-Rahman, Mohamed A.
Although scorpions are most common and diverse in deserts, Main Features : Maurocalcine is a 33-mer basic peptide cross-linked by three disulphide bridges , synthetic, originally from Scorpio maurus palmatus scorpion venom. AU - Omran, Mohamed Alaa A. It is an activator of Ca2+ release channel and so a Ryanodine receptors agonist. S. maurus palmatus venom (30 μg/ml) impaired HCV infectivity in culture medium, but not inside the cells, through virocidal effect. Scorpio maurus is a species of North African and Middle Eastern scorpion, also known as the large-clawed scorpion or Israeli gold scorpion. PY - 2009/3/1. Y1 - 2009/3/1 To further explore the mode of action of the S. maurus palmatus venom, time-of-addition experiments were performed.
Chlorotoxin from the deathstalker scorpion (Leiurus quinquestriatus); the toxin blocks small-conductance chloride channels; Maurotoxin from the venom of the Tunisian Scorpio maurus blocks potassium channels. LATOXAN is the world exclusive source of this toxin. Some, such as Prionurus australis, are able to kill children, and even adults, by their sting; others, such as Scorpio maurus have never been known to cause death.
A więc można się spodziewać, że będzie to wyglądać nieco inaczej niż w … Hepatitis C virus (HCV) and dengue virus (DENV) belong to the Flaviviridae family and are an increasing global health threat. Growing global viral infections have been a serious public health problem in recent years. 2009;53(3):349–59. This current situation emphasizes the importance of developing more therapeutic antiviral compounds. Polowanie w wykonaniu Scorpio maurus, przedstawiciela rodziny Scorpionidae. PubMed CrossRef Google Scholar Scorpion, (order Scorpiones or Scorpionida), any of approximately 1,500 elongated arachnid species characterized by a segmented curved tail tipped with a venomous stinger at the rear of the body and a pair of grasping pincers at the front.
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